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Allele : Dnah10<em1Yxc> dynein, axonemal, heavy chain 10; endonuclease-mediated mutation 1, Yunxia Cao

Primary Identifier  MGI:6780038 Allele Type  Endonuclease-mediated
Attribute String  Null/knockout Gene  Dnah10
Strain of Origin  C57BL/6 Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/cas9 mediated recombination using 2 guide RNAs (sgRNA-1: ATCTTATGCTGGGTCCAGTAAGG, sgRNA-2: TTTATAACAAATGGCTTGATTGG) deleted a genomic region spanning exons 2 - 5. Immunostaining confirmed the absence of protein expression in testes and spermatozoa from homozygous mice.
  • mutations:
  • Intragenic deletion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Genotypes/models

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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3 Publication categories