| Primary Identifier | MGI:7482648 | Allele Type | Endonuclease-mediated |
| Attribute String | Inducible, Recombinase | Gene | Cdkn1c |
| Transmission | Germline | Strain of Origin | Not Specified |
| Induced With | tamoxifen | Is Recombinase | true |
| Is Wild Type | false |
| molecularNote | Using CRISPR/Cas9 system, the T2A-cre/ERT2 cassette was inserted in-frame into the endogenous Cdkn1c (p57) coding sequence immediately 5������ to the only TGA codon at this locus in ES cells. Single colony ES cell clones that had undergone homologous recombination were then expanded and injected into C57BL/6 mouse blastocysts to generate chimeric mice. |
