| Primary Identifier | MGI:8224283 | Allele Type | Transgenic |
| Attribute String | Recombinase | Gene | Tg(Sost-cre/ERT2)2Bwd |
| Strain of Origin | C57BL/6N | Is Recombinase | true |
| Is Wild Type | false |
| molecularNote | Usinga mouse RP24-178J4 BAC (157Kb) containing the Sost gene, recombineering was used to replace the ATG region of Sost with a Cre/ERT2 cassette. This construct was then used to generate transgenic mice. Of four lines generated, only line #2 showed strong and consistent Cre recombination in osteocytes following tamoxifen treatment and was analyzed futher. |
