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Allele : Gt(ROSA)26Sor<tm1(Nfkb-dEGFP*)Kopf> gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Manfred Kopf

Primary Identifier  MGI:8226103 Allele Type  Targeted
Attribute String  Reporter Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  C57BL/6NHsd
Is Recombinase  false Is Wild Type  false
molecularNote  Eight copies of an octameric NF-����B response element is placed upstream of a destabilized version of EGFP containing a C-terminal PEST domain (destEGFP), which considerably reduces the half-life of EGFP and the background fluorescence in the absence of an activating stimulus. This construct was inserted into the Gt(ROSA)26Sor locus. Mice carrying this allele report specific NF-kappaB transcriptional activity.
  • mutations:
  • Insertion
  • synonyms:
  • Gt(ROSA)26Sor<tm1(Nfkb-destEGFP)Kopf>,
  • Gt(ROSA)26Sor<tm1(Nfkb-destEGFP)Kopf>,
  • KappaBle,
  • KappaBle
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Genotypes/models

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories