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Allele : Fbn1<tm1(FBN1)Cya> fibrillin 1; targeted mutation 1, Cyagen Biosciences
Primary Identifier  MGI:8235563 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Fbn1
Transmission  Germline Strain of Origin  C57BL/6JCya
Is Recombinase  false Is Wild Type  false
molecularNote  The sequence from amino acid 25 to ~600 bp downstream of the 3'UTR of mouse Fbn1 was replaced with the sequence from amino acid 25 to ~600 bp downstream of the 3'UTR of human FBN1. The murine signal peptide (amino acid 1~24) was kept.
  • mutations:
  • Insertion
  • synonyms:
  • Fbn1<tm1(hFBN1)>,
  • Fbn1<tm1(hFBN1)>
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Genotypes/models

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories





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