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Allele : Mllt1<em1Wenh> myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1; endonuclease-mediated mutation 1, Hong Wen

Primary Identifier  MGI:8242304 Allele Type  Endonuclease-mediated
Attribute String  Conditional ready Gene  Mllt1
Inheritance Mode  Not Specified Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR-targeting of inserted a loxP site upstream of the endogenous exon 4 and fused the remaining sequencing sequence in frame following by a loxP site and a modified exon 4 (T1 modification of the YEATS domain NPPVNHLR to NPPVNHLNHLR). This allele mimics a mutation found in Wilms tumors from patients.
  • mutations:
  • Insertion
  • synonyms:
  • Enl<T1-fl>,
  • Enl<T1-fl>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Genotypes/models

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories