|  Help  |  About  |  Contact Us

Allele : Gt(ROSA)26Sor<tm2(EWSR1/KLF15)Cklr> gene trap ROSA 26, Philippe Soriano; targeted mutation 2, Charles Keller

Primary Identifier  MGI:8270517 Allele Type  Targeted
Attribute String  Conditional ready, Inserted expressed sequence Gene  Gt(ROSA)26Sor
Transmission  Germline Strain of Origin  C57BL/6J
Is Recombinase  false Is Wild Type  false
molecularNote  The allele contains (from 5' to 3') a loxP site, a neomycin resistance (neo) cassette, a lox2272 site, a human Ewing sarcoma breakpoint region 1 fusion (EWSR1) cDNA fused to a human Kruppel-like transcription factor 15 (KLF15) cDNA with a polyadenylation signal, and second loxP and lox2272 sites in opposite orientations to their companion lox sites. The EWSR1::KLF15 fusion sequence is inserted in opposite orientation to the endogenous Gt(ROSA)26Sor gene.
  • mutations:
  • Insertion
Quick Links:
 
Quick Links:
 

1 Feature

Genome

2 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Genotypes/models

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

3 Publication categories