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DO Term : T2-low asthma [DOID:0080818] Disease Ontology

Namespace  disease_ontology Obsolete  false
description  A chronic asthma that is characterized by the pathophysiology phenotype combination (endotype) of non-atopic, smoking, obesity related, and elderly and that is characterized by neutrophilic (sputum neutrophils > 40–60%) or paucigranulocytic (i.e., normal sputum levels of both eosinophils and neutrophils) inflammation and a lack of response to corticosteroid therapy.
  • synonyms:
  • type 2 low endotype
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