| Namespace | MPheno.ontology | Obsolete | false |
| description | any anomaly in the migratory path or behavior of the neural crest cells (NCCs) that arise from the sacral region of the neural tube (sacral neural crest), caudal to somite 28, and migrate caudo-rostrally to contribute to a small fraction of enteric neurons and glia in the distal midgut and hindgut; in the mouse, sacral NCCs emigrate from the neural tube at E9.5, accumulate bilateral to the hindgut to form prospective pelvic ganglia at E11.5, and from there enter the distal hindgut through its ventrolateral side at E13.5; they then migrate along nerve fibers extending from the pelvic ganglia toward the proximal hindgut, intermingling with rostrocaudally migrating vagal NCCs to differentiate into neurons and glia |
