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GO Term : symbiont-mediated suppression of host PKR/eIFalpha signaling [GO:0039580] Gene Ontology

Namespace  biological_process Obsolete  false
description  A process in which a symbiont inhibits or disrupts host PKR (Protein Kinase regulated by RNA) signaling. PKR phosphorylates host targets such as the translation initiation factor eIF2alpha that inhibits protein synthesis as an antimicrobial response. Inhibition of host PKR signaling maintains the host ability to translate mRNA. The host is defined as the larger of the organisms involved in a symbiotic interaction.
  • synonyms:
  • suppression by virus of host EIF2AK2 activity,
  • suppression by virus of host PKR signaling,
  • suppression by virus of host PKR activity
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Function

Functions (GO terms and children) --> Mouse features

Functions (GO terms) --> Mouse features

Ontology

Ontology Term --> All ancestors

Ontology Term --> All descendants

Ontology Term --> Direct children

Ontology Term --> Direct parents