Any process that stops or reduces the rate of cyclic nucleotide phosphodiesterase activity, the catalysis of the reaction: nucleotide 3',5'-cyclic phosphate + H2O = nucleotide 5'-phosphate.
synonyms:
down regulation of cyclic nucleotide phosphodiesterase activity,
phosphodiesterase inhibitor,
cAMP phosphodiesterase inhibitor,
3',5'-cyclic-AMP phosphodiesterase inhibitor,
negative regulation of cyclic nucleotide phosphodiesterase activity,
inhibition of cyclic nucleotide phosphodiesterase activity,
negative regulation of 3',5'-cyclic-AMP phosphodiesterase activity,
down-regulation of cyclic nucleotide phosphodiesterase activity,
downregulation of cyclic nucleotide phosphodiesterase activity,
negative regulation of 3',5' cyclic nucleotide phosphodiesterase activity,
