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Publication : Analysis of the mouse MAP1B gene identifies a highly conserved 4.3 kb 3' untranslated region and provides evidence against the proposed structure of DBI-1 cDNA.

First Author  Meixner A Year  1999
Journal  Biochim Biophys Acta Volume  1445
Issue  3 Pages  345-50
PubMed ID  10366719 Mgi Jnum  J:55711
Mgi Id  MGI:1339239 Doi  10.1016/s0167-4781(99)00062-7
Citation  Meixner A, et al. (1999) Analysis of the mouse MAP1B gene identifies a highly conserved 4.3 kb 3' untranslated region and provides evidence against the proposed structure of DBI-1 cDNA. Biochim Biophys Acta 1445(3):345-50
abstractText  We determined the previously unknown 3' end of MAP1B mRNA. We found an unusually long and highly conserved 3' untranslated region (3'UTR) of 4.3 kb and detected a polymorphism in the 3' flanking region probably due to the integration of an endogenous retroviral MuERV-L element. Furthermore, we found that MAP1B 3'UTR overlapped with the 5' end of the cDNA encoding DBI-1. However, further analysis suggested that the published structure of DBI-1 cDNA is most likely the result of fortuitous joining of unrelated cDNA fragments during cloning.
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