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Search results 201 to 300 out of 2079 for Lck

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Type Details Score
GXD Expression
GXD Expression
   
Probe: MGI:5617767
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1679820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5618102
Age: embryonic day 12.5
Specimen Label: not shown E12
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5617767
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689420
Pattern: Uniform
Stage: TS20
Assay Id: MGI:5618102
Age: embryonic day 12.5
Specimen Label: not shown E12
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5617767
Assay Type: Immunohistochemistry
Annotation Date: 2015-03-10
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1689417
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5618102
Age: embryonic day 10.5
Specimen Label: not shown E10
Detected: true
Specimen Num: 4
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Publication
1279202 | -
First Author: Hurley TR
Year: 1992
Journal: J Virol
Title: Creation and characterization of temperature-sensitive mutants of the lck tyrosine protein kinase.
Volume: 66
Issue: 12
Pages: 7406-13
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Publication
10553045 | J:58458
First Author: Choi YB
Year: 1999
Journal: J Immunol
Title: Lad, an adapter protein interacting with the SH2 domain of p56lck, is required for T cell activation.
Volume: 163
Issue: 10
Pages: 5242-9
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Publication
24101551 | J:206334
First Author: Engelmann S
Year: 2013
Journal: J Immunol
Title: T cell-independent modulation of experimental autoimmune encephalomyelitis in ADAP-deficient mice.
Volume: 191
Issue: 10
Pages: 4950-9
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Publication
20007709 | J:165958
First Author: Choi YB
Year: 2010
Journal: J Biol Chem
Title: SOCS-6 negatively regulates T cell activation through targeting p56lck to proteasomal degradation.
Volume: 285
Issue: 10
Pages: 7271-80
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Publication
18976935 | J:143773
First Author: Bécart S
Year: 2008
Journal: Immunity
Title: Tyrosine-phosphorylation-dependent translocation of the SLAT protein to the immunological synapse is required for NFAT transcription factor activation.
Volume: 29
Issue: 5
Pages: 704-19
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Publication
15128794 | J:89871
First Author: Gadue P
Year: 2004
Journal: J Immunol
Title: Restoration of NK T cell development in fyn-mutant mice by a TCR reveals a requirement for Fyn during early NK T cell ontogeny.
Volume: 172
Issue: 10
Pages: 6093-100
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Publication
7761462 | J:25724
First Author: Pineau T
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Neonatal lethality associated with respiratory distress in mice lacking cytochrome P450 1A2.
Volume: 92
Issue: 11
Pages: 5134-8
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Publication
20826747 | J:164287
First Author: Chrobak P
Year: 2010
Journal: J Immunol
Title: HIV-1 Nef disrupts maturation of CD4+ T cells through CD4/Lck modulation.
Volume: 185
Issue: 7
Pages: 3948-59
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Publication
10072519 | J:110847
First Author: Würch A
Year: 1999
Journal: J Immunol
Title: Reduced generation but efficient TCR beta-chain selection of CD4+8+ double-positive thymocytes in mice with compromised CD3 complex signaling.
Volume: 162
Issue: 5
Pages: 2741-7
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Publication
14752163 | J:90029
First Author: Hasegawa K
Year: 2004
Journal: Science
Title: PEST domain-enriched tyrosine phosphatase (PEP) regulation of effector/memory T cells.
Volume: 303
Issue: 5658
Pages: 685-9
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Publication
10097132 | J:123031
First Author: Biro J
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Regulation of T cell receptor (TCR) beta gene expression by CD3 complex signaling in immature thymocytes: implications for TCRbeta allelic exclusion.
Volume: 96
Issue: 7
Pages: 3882-7
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Publication
8171035 | J:18261
First Author: Drake CG
Year: 1994
Journal: Proc Natl Acad Sci U S A
Title: Genetic analysis of the NZB contribution to lupus-like autoimmune disease in (NZB x NZW)F1 mice.
Volume: 91
Issue: 9
Pages: 4062-6
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Publication
15210755 | J:90818
First Author: Krotkova A
Year: 2004
Journal: J Immunol
Title: Delayed and restricted expression limits putative instructional opportunities of Vgamma1.1/Vgamma2 gammadelta TCR in alphabeta/gammadelta lineage choice in the thymus.
Volume: 173
Issue: 1
Pages: 25-32
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Publication
14749125 | J:87942
First Author: Zhao R
Year: 2004
Journal: Cancer Cell
Title: An oncogenic tyrosine kinase inhibits DNA repair and DNA-damage-induced Bcl-xL deamidation in T cell transformation.
Volume: 5
Issue: 1
Pages: 37-49
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Publication
24311692 | J:205261
First Author: de la Roche M
Year: 2013
Journal: Science
Title: Hedgehog signaling controls T cell killing at the immunological synapse.
Volume: 342
Issue: 6163
Pages: 1247-50
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Publication
11470773 | J:71151
First Author: Baur N
Year: 2001
Journal: Int Immunol
Title: Expression and selection of productively rearranged TCR beta VDJ genes are sequentially regulated by CD3 signaling in the development of NK1.1(+) alpha beta T cells.
Volume: 13
Issue: 8
Pages: 1031-42
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Publication
9802979 | J:112046
First Author: Würch A
Year: 1998
Journal: J Exp Med
Title: Requirement of CD3 complex-associated signaling functions for expression of rearranged T cell receptor beta VDJ genes in early thymic development.
Volume: 188
Issue: 9
Pages: 1669-78
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Publication
9725213 | J:111646
First Author: Yada S
Year: 1998
Journal: J Immunol
Title: Differential requirements of CD45 protein tyrosine phosphatase for cytolytic activities and intrathymic and extrathymic development of intestinal intraepithelial lymphocytes.
Volume: 161
Issue: 5
Pages: 2208-16
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Publication
9870664 | J:52164
First Author: Sato T
Year: 1998
Journal: Immunol Lett
Title: Beta-selection of immature thymocytes is less dependent on CD45 tyrosinephosphatase.
Volume: 64
Issue: 2-3
Pages: 133-8
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Publication
7486703 | J:166038
 
First Author: Campbell KS
Year: 1995
Journal: Ann N Y Acad Sci
Title: Interaction of p56lck with CD4 in the yeast two-hybrid system.
Volume: 766
Pages: 89-92
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Publication
9581568 | J:200350
 
First Author: Ng DH
Year: 1997
Journal: Biochem J
Title: CD45 and RPTPalpha display different protein tyrosine phosphatase activities in T lymphocytes.
Volume: 327 ( Pt 3)
Pages: 867-76
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Publication
15121848 | J:89892
First Author: Canela A
Year: 2004
Journal: Mol Cell Biol
Title: Constitutive expression of tert in thymocytes leads to increased incidence and dissemination of T-cell lymphoma in Lck-Tert mice.
Volume: 24
Issue: 10
Pages: 4275-93
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Publication
15522954 | J:98143
First Author: Nie G
Year: 2005
Journal: Blood
Title: Overexpression of mitochondrial ferritin causes cytosolic iron depletion and changes cellular iron homeostasis.
Volume: 105
Issue: 5
Pages: 2161-7
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Publication
20498282 | J:162651
First Author: Hashimoto-Tane A
Year: 2010
Journal: Mol Cell Biol
Title: T-cell receptor microclusters critical for T-cell activation are formed independently of lipid raft clustering.
Volume: 30
Issue: 14
Pages: 3421-9
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Publication
25605905 | J:217665
First Author: Wang T
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Real-time resolution of point mutations that cause phenovariance in mice.
Volume: 112
Issue: 5
Pages: E440-9
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Publication
8806656 | J:35262
First Author: Ishii T
Year: 1996
Journal: Biochem Biophys Res Commun
Title: Murine peritoneal macrophages induce a novel 60-kDa protein with structural similarity to a tyrosine kinase p56lck-associated protein in response to oxidative stress.
Volume: 226
Issue: 2
Pages: 456-60
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Publication
20974990 | J:167365
First Author: Laird RM
Year: 2010
Journal: J Immunol
Title: Unexpected role for the B cell-specific Src family kinase B lymphoid kinase in the development of IL-17-producing γδ T cells.
Volume: 185
Issue: 11
Pages: 6518-27
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Publication
12759418 | J:85823
First Author: Matsuki N
Year: 2003
Journal: J Immunol
Title: Genetic dissection of V alpha 14J alpha 18 natural T cell number and function in autoimmune-prone mice.
Volume: 170
Issue: 11
Pages: 5429-37
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Publication
8521470 | J:29509
First Author: Griff IC
Year: 1995
Journal: Cell
Title: The genetic basis for specific anosmia to isovaleric acid in the mouse.
Volume: 83
Issue: 3
Pages: 407-14
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Publication
- | J:21662
     
First Author: Wallace VA
Year: 1994
Title: T-Cell development in CD4, CD8, and p56(lck) Gene-Targeted mice.
Pages: 67-81
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Publication
7664803 | J:115170
First Author: Campbell KS
Year: 1995
Journal: Eur J Immunol
Title: Interactions between the amino-terminal domain of p56lck and cytoplasmic domains of CD4 and CD8 alpha in yeast.
Volume: 25
Issue: 8
Pages: 2408-12
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Publication
19109140 | J:142904
First Author: Nazarov-Stoica C
Year: 2009
Journal: J Immunol
Title: CD28 signaling in T regulatory precursors requires p56lck and rafts integrity to stabilize the Foxp3 message.
Volume: 182
Issue: 1
Pages: 102-10
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Publication
23427257 | J:194752
First Author: Borger JG
Year: 2013
Journal: J Immunol
Title: Differential polarization of C-terminal Src kinase between naive and antigen-experienced CD8+ T cells.
Volume: 190
Issue: 7
Pages: 3089-99
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Publication
8551236 | J:35635
First Author: Fournel M
Year: 1996
Journal: J Exp Med
Title: Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes.
Volume: 183
Issue: 1
Pages: 301-6
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Publication
8661721 | J:33171
First Author: Wu C
Year: 1996
Journal: Mamm Genome
Title: Mouse uroporphyrinogen decarboxylase: cDNA cloning, expression, and mapping.
Volume: 7
Issue: 5
Pages: 349-52
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Publication
14706337 | J:88120
First Author: Sicinska E
Year: 2003
Journal: Cancer Cell
Title: Requirement for cyclin D3 in lymphocyte development and T cell leukemias.
Volume: 4
Issue: 6
Pages: 451-61
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Publication
10453000 | J:57092
First Author: Chu DH
Year: 1999
Journal: J Immunol
Title: Pre-T cell receptor signals are responsible for the down-regulation of Syk protein tyrosine kinase expression.
Volume: 163
Issue: 5
Pages: 2610-20
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Publication
12077322 | J:126523
First Author: Huang J
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: CD28 plays a critical role in the segregation of PKC theta within the immunologic synapse.
Volume: 99
Issue: 14
Pages: 9369-73
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Publication
19668367 | J:152472
First Author: Kim JK
Year: 2009
Journal: PLoS One
Title: Impact of the TCR signal on regulatory T cell homeostasis, function, and trafficking.
Volume: 4
Issue: 8
Pages: e6580
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Publication
10940892 | J:63511
First Author: Qu WM
Year: 2000
Journal: Eur J Immunol
Title: Genetic dissection of vasculitis in MRL/lpr lupus mice: a novel susceptibility locus involving the CD72c allele.
Volume: 30
Issue: 7
Pages: 2027-37
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Publication
9002646 | J:134589
First Author: Guimond MJ
Year: 1997
Journal: Biol Reprod
Title: Absence of natural killer cells during murine pregnancy is associated with reproductive compromise in TgE26 mice.
Volume: 56
Issue: 1
Pages: 169-79
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Publication
7648394 | J:28295
First Author: Levelt CN
Year: 1995
Journal: Immunity
Title: Regulation of thymocyte development through CD3: functional dissociation between p56lck and CD3 sigma in early thymic selection.
Volume: 3
Issue: 2
Pages: 215-22
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Publication
7807014 | J:22470
First Author: Kawai K
Year: 1995
Journal: J Exp Med
Title: Impaired development of V gamma 3 dendritic epidermal T cells in p56lck protein tyrosine kinase-deficient and CD45 protein tyrosine phosphatase-deficient mice.
Volume: 181
Issue: 1
Pages: 345-9
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Publication
9177270 | J:40461
First Author: Sammar M
Year: 1997
Journal: Biochem Biophys Res Commun
Title: Mouse CD24 as a signaling molecule for integrin-mediated cell binding: functional and physical association with src-kinases.
Volume: 234
Issue: 2
Pages: 330-4
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Publication
7499277 | J:29834
First Author: Katagiri T
Year: 1995
Journal: J Biol Chem
Title: Selective regulation of Lyn tyrosine kinase by CD45 in immature B cells.
Volume: 270
Issue: 47
Pages: 27987-90
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Publication
10713104 | J:116375
First Author: Ingley E
Year: 2000
Journal: J Biol Chem
Title: HS1 interacts with Lyn and is critical for erythropoietin-induced differentiation of erythroid cells.
Volume: 275
Issue: 11
Pages: 7887-93
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Publication
8143742 | J:18014
First Author: Ito Y
Year: 1994
Journal: Eur J Biochem
Title: Structural analysis of the functional gene and pseudogene encoding the murine granulocyte colony-stimulating-factor receptor.
Volume: 220
Issue: 3
Pages: 881-91
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Publication
7719022 | J:22428
First Author: Truett GE
Year: 1995
Journal: Mamm Genome
Title: Genetic map of rat chromosome 5 including the fatty (fa) locus.
Volume: 6
Issue: 1
Pages: 25-30
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Publication
8522158 | J:29528
First Author: Lush IE
Year: 1995
Journal: Genet Res
Title: The genetics of tasting in mice. VII. Glycine revisited, and the chromosomal location of Sac and Soa.
Volume: 66
Issue: 2
Pages: 167-74
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Publication
15634756 | J:95303
First Author: Fleischer A
Year: 2004
Journal: Mol Cancer Res
Title: Bad-dependent rafts alteration is a consequence of an early intracellular signal triggered by interleukin-4 deprivation.
Volume: 2
Issue: 12
Pages: 674-84
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Publication
8074710 | J:20474
First Author: Sakagami T
Year: 1994
Journal: Biochem Biophys Res Commun
Title: Structure and chromosomal locus of the mouse gene encoding a cerebellar Purkinje cell-specific helix-loop-helix factor Hes-3.
Volume: 203
Issue: 1
Pages: 594-601
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Publication
7926807 | J:20871
First Author: Treuner M
Year: 1994
Journal: Gene
Title: Cloning and characterization of the mouse gene encoding mammary-derived growth inhibitor/heart-fatty acid-binding protein.
Volume: 147
Issue: 2
Pages: 237-42
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Publication
11744391 | J:73819
First Author: Ohtoshi A
Year: 2002
Journal: Mech Dev
Title: Dmbx1, a novel evolutionarily conserved paired-like homeobox gene expressed in the brain of mouse embryos.
Volume: 110
Issue: 1-2
Pages: 241-4
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Publication
2000388 | J:13202
First Author: Christy BA
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: An Id-related helix-loop-helix protein encoded by a growth factor-inducible gene.
Volume: 88
Issue: 5
Pages: 1815-9
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Publication
2404338 | J:10210
First Author: Dymecki SM
Year: 1990
Journal: Science
Title: Specific expression of a tyrosine kinase gene, blk, in B lymphoid cells.
Volume: 247
Issue: 4940
Pages: 332-6
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Publication
8415697 | J:15237
First Author: Bzdega T
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Regional expression and chromosomal localization of the delta opiate receptor gene.
Volume: 90
Issue: 20
Pages: 9305-9
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Publication
8363569 | J:14351
 
First Author: Bell DR
Year: 1993
Journal: Biochem J
Title: Species-specific induction of cytochrome P-450 4A RNAs: PCR cloning of partial guinea-pig, human and mouse CYP4A cDNAs.
Volume: 294 ( Pt 1)
Pages: 173-80
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Publication
10358158 | J:55529
First Author: Thien CB
Year: 1999
Journal: J Immunol
Title: Perturbed regulation of ZAP-70 and sustained tyrosine phosphorylation of LAT and SLP-76 in c-Cbl-deficient thymocytes.
Volume: 162
Issue: 12
Pages: 7133-9
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Publication
9366400 | J:44075
First Author: Lesage S
Year: 1997
Journal: J Immunol
Title: CD4+ CD8+ thymocytes are preferentially induced to die following CD45 cross-linking, through a novel apoptotic pathway.
Volume: 159
Issue: 10
Pages: 4762-71
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Publication
11870621 | J:108602
First Author: Lowin-Kropf B
Year: 2002
Journal: Eur J Immunol
Title: A role for the src family kinase Fyn in NK cell activation and the formation of the repertoire of Ly49 receptors.
Volume: 32
Issue: 3
Pages: 773-82
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Publication
20844195 | J:164883
First Author: Visan I
Year: 2010
Journal: J Immunol
Title: Lunatic fringe enhances competition for delta-like Notch ligands but does not overcome defective pre-TCR signaling during thymocyte beta-selection in vivo.
Volume: 185
Issue: 8
Pages: 4609-17
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Publication
26416283 | J:243470
First Author: Xiao Y
Year: 2015
Journal: J Immunol
Title: Protein Tyrosine Phosphatase SHP-1 Modulates T Cell Responses by Controlling Cbl-b Degradation.
Volume: 195
Issue: 9
Pages: 4218-27
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Publication
18069898 | J:133427
First Author: Garrett-Engele CM
Year: 2007
Journal: PLoS Genet
Title: A mechanism misregulating p27 in tumors discovered in a functional genomic screen.
Volume: 3
Issue: 12
Pages: e219
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Publication
9390273 | J:44588
 
First Author: Lai WC
Journal: Nat Immun
Title: Natural resistance to Mycoplasma pulmonis infection in mice: host resistance gene(s) map to chromosome 4.
Volume: 15
Issue: 5
Pages: 241-8
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Publication
1675432 | J:3351
First Author: Todd JA
Year: 1991
Journal: Nature
Title: Genetic analysis of autoimmune type 1 diabetes mellitus in mice.
Volume: 351
Issue: 6327
Pages: 542-7
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Publication
1978328 | J:10819
First Author: Bahary N
Year: 1990
Journal: Proc Natl Acad Sci U S A
Title: Molecular mapping of the mouse db mutation.
Volume: 87
Issue: 21
Pages: 8642-6
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Publication
9169414 | J:40949
First Author: Takaki S
Year: 1997
Journal: J Biol Chem
Title: Characterization of Lnk. An adaptor protein expressed in lymphocytes.
Volume: 272
Issue: 23
Pages: 14562-70
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Publication
11254359 | J:68671
First Author: Ilan N
Year: 2001
Journal: Dev Biol
Title: Pecam-1 is a modulator of stat family member phosphorylation and localization: lessons from a transgenic mouse.
Volume: 232
Issue: 1
Pages: 219-32
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Publication
3166417 | J:4474
 
First Author: Huppi K
Year: 1988
Journal: Curr Top Microbiol Immunol
Title: Organization of the distal end of mouse chromosome 4.
Volume: 137
Pages: 276-88
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Publication
1643308 | J:1713
First Author: McAleer MA
Year: 1992
Journal: Mamm Genome
Title: Linkage analysis of 84 microsatellite markers in intra- and interspecific backcrosses.
Volume: 3
Issue: 8
Pages: 457-60
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Publication
8098006 | J:4362
First Author: Bahary N
Year: 1993
Journal: Genomics
Title: Microdissection and microcloning of mid-chromosome 4: genetic mapping of 41 microdissection clones.
Volume: 16
Issue: 1
Pages: 113-22
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Publication
8104199 | J:14517
First Author: Berry MJ
Year: 1993
Journal: J Clin Invest
Title: Physiological and genetic analyses of inbred mouse strains with a type I iodothyronine 5' deiodinase deficiency.
Volume: 92
Issue: 3
Pages: 1517-28
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Publication
7719023 | J:22430
First Author: Stoye JP
Year: 1995
Journal: Mamm Genome
Title: Genetic map of the region surrounding the retrovirus restriction locus, Fv1, on mouse chromosome 4.
Volume: 6
Issue: 1
Pages: 31-6
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Publication
7536925 | J:24355
First Author: Alexandropoulos K
Year: 1995
Journal: Proc Natl Acad Sci U S A
Title: Proline-rich sequences that bind to Src homology 3 domains with individual specificities.
Volume: 92
Issue: 8
Pages: 3110-4
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Publication
8415706 | J:15180
First Author: Sato TN
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Tie-1 and tie-2 define another class of putative receptor tyrosine kinase genes expressed in early embryonic vascular system.
Volume: 90
Issue: 20
Pages: 9355-8
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Publication
2037292 | J:11192
First Author: Fletcher C
Year: 1991
Journal: Genomics
Title: Genetic mapping of meander tail, a mouse mutation affecting cerebellar development.
Volume: 9
Issue: 4
Pages: 647-55
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Publication
2574141 | J:10133
First Author: Ceci JD
Year: 1989
Journal: Genomics
Title: A molecular genetic linkage map of mouse chromosome 4 including the localization of several proto-oncogenes.
Volume: 5
Issue: 4
Pages: 699-709
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Publication
7949731 | J:20039
First Author: Fiedorek FT Jr
Year: 1994
Journal: Mamm Genome
Title: Mapping of PCR-based markers for mouse chromosome 4 on a backcross penetrant for the misty (m) mutation.
Volume: 5
Issue: 8
Pages: 479-85
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Publication
7829080 | J:20147
First Author: McClive PJ
Year: 1994
Journal: Genomics
Title: Assignment of the mouse homologues of 6 loci from HSA1p to chromosomes 3 and 4.
Volume: 23
Issue: 1
Pages: 243-6
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Publication
- | J:55945
First Author: Wang JP
Year: 1998
Journal: Biomed Res
Title: Expression of Src family during development of the mouse nervous system.
Volume: 19
Issue: 5
Pages: 315-325
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Publication
22683124 | J:187430
First Author: Dong Z
Year: 2012
Journal: Immunity
Title: The adaptor SAP controls NK cell activation by regulating the enzymes Vav-1 and SHIP-1 and by enhancing conjugates with target cells.
Volume: 36
Issue: 6
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