| Primary Identifier | MGI:88264 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 12334 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables calcium-dependent cysteine-type endopeptidase activity. Involved in several processes, including cellular response to amino acid stimulus; protein catabolic process at postsynapse; and synaptic vesicle endocytosis. Acts upstream of or within blastocyst development and myoblast fusion. Located in several cellular components, including chromatin; cytosol; and lysosome. Is active in postsynapse. Is expressed in several structures, including central nervous system; lens epithelium; molar; oral region epithelium; and skin. Orthologous to human CAPN2 (calpain 2). PHENOTYPE: Homozygous inactivation of this gene leads to complete prenatal lethality. Mice homozygous for one null allele display placental dysfunction, thin ventricular walls, and peripheral vessel failure. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
