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Protein Coding Gene : Rab1a RAB1A, member RAS oncogene family
Primary Identifier  MGI:97842 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  19324
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable GTP binding activity and GTPase activity. Involved in cell migration; melanosome transport; and substrate adhesion-dependent cell spreading. Located in Golgi apparatus and melanosome. Is expressed in several structures, including diaphragm and genitourinary system. Used to study dilated cardiomyopathy. Orthologous to human RAB1A (RAB1A, member RAS oncogene family).
PHENOTYPE: Mice homozygous for a null allele exhibit complete embryonic lethality during organogenesis. [provided by MGI curators]
  • synonyms:
  • MGD-MRK-15847,
  • RAB1A, member RAS oncogene family,
  • Ypt1,
  • Rab1a,
  • members RAS oncogene family,
  • name unknown at this time 12/9/92,
  • ypt-1 ras-related GTP binding protein,
  • Rab1,
  • MGD-MRK-10329,
  • ras-related YPT1 protein,
  • MGD-MRK-13744,
  • RAB1, member RAS oncogene family,
  • Rab-1,
  • mKIAA3012,
  • Gtbp,
  • MGD-MRK-13745
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1 Involved In Mutations

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3 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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Genes --> Homologs

Interactions

20 Pathways

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Gene --> Protein-Protein Interactions

Expression

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Phenotype

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Disease

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