| Primary Identifier | MGI:102890 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 12450 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable cyclin-dependent protein serine/threonine kinase regulator activity. Predicted to be involved in several processes, including G1/S transition of mitotic cell cycle; mitotic G2 DNA damage checkpoint signaling; and syncytium formation. Predicted to be located in dendrite; neuronal cell body; and perinuclear region of cytoplasm. Predicted to be part of cyclin-dependent protein kinase holoenzyme complex. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; immune system; and liver and biliary system. Human ortholog(s) of this gene implicated in endocrine gland cancer (multiple); localized osteosarcoma; ovarian cancer (multiple); and sarcoma. Orthologous to human CCNG1 (cyclin G1). PHENOTYPE: Depending on the allele, homozygous mutants exhibit increased cellular sensitivity to gamma-irradiation or decreased incidence of induced hepatic tumors. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
