Primary Identifier | MGI:1197526 | Organism | mouse, laboratory |
Chromosome | 13 | NCBI Gene Number | 16372 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in proximal/distal pattern formation involved in metanephric nephron development and specification of loop of Henle identity. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; autopod; central nervous system; genitourinary system; and respiratory system. Orthologous to human IRX2 (iroquois homeobox 2). PHENOTYPE: Mice homozygous for disruptions in this gene are phenotypically normal. [provided by MGI curators] |