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Protein Coding Gene : Clic1 chloride intracellular channel 1
Primary Identifier  MGI:2148924 Organism  mouse, laboratory
Chromosome  17 NCBI Gene Number  114584
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Predicted to enable chloride channel activity. Acts upstream of or within positive regulation of osteoblast differentiation and regulation of mitochondrial membrane potential. Located in mitochondrion and nucleus. Is expressed in brain; early conceptus; and heart valve. Orthologous to human CLIC1 (chloride intracellular channel 1).
PHENOTYPE: Mice homozygous for disruptions in this gene display abnormal platelet number, activation and aggregation and prolonged bleeding time. [provided by MGI curators]
  • synonyms:
  • chloride intracellular channel 1,
  • G6,
  • Clic1,
  • Clcp
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