Primary Identifier | MGI:1333757 | Organism | mouse, laboratory |
Chromosome | 17 | NCBI Gene Number | 268980 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including armadillo repeat domain binding activity; calmodulin binding activity; and nuclear estrogen receptor binding activity. Predicted to be involved in several processes, including Wnt signaling pathway; dendrite development; and locomotory behavior. Predicted to be located in several cellular components, including bicellular tight junction; dendritic spine; and postsynaptic membrane. Predicted to be part of FAR/SIN/STRIPAK complex. Predicted to be active in dendrite. Is expressed in central nervous system and retina. Orthologous to human STRN (striatin). PHENOTYPE: Mice heterozygous for a knock-out allele exhibit increased blood pressure and circulating aldosterone when fed a liberal salt diet. No mice could be generated that were homozygous for the allele. [provided by MGI curators] |