Primary Identifier | MGI:1929704 | Organism | mouse, laboratory |
Chromosome | 18 | NCBI Gene Number | 59057 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables sequence-specific DNA binding activity. Involved in myelination. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; limb primordium; and sensory organ. Orthologous to human ZNF24 (zinc finger protein 24). PHENOTYPE: Mice homozygous null for one mutation have hypomyelination of the central nervous system, tremors, tonic seizures and premature death, whereas mice homozygous null for another mutation are embryonic lethal. [provided by MGI curators] |