Primary Identifier | MGI:96568 | Organism | mouse, laboratory |
Chromosome | 19 | NCBI Gene Number | 226180 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) A structural constituent of postsynaptic intermediate filament cytoskeleton. Involved in postsynaptic modulation of chemical synaptic transmission. Acts upstream of or within cellular response to leukemia inhibitory factor and neurofilament cytoskeleton organization. Located in neurofilament. Is active in Schaffer collateral - CA1 synapse and postsynapse. Is expressed in several structures, including central nervous system; gut; peripheral nervous system ganglion; sensory organ; and trigeminal nerve. Orthologous to human INA (internexin neuronal intermediate filament protein alpha). PHENOTYPE: Homozygous mice are healthy and viable, and do not exhibit any obvious abnormalities; no defects in the nervous system were detected, including brain development, axon outgrowth, or guidance. [provided by MGI curators] |