Primary Identifier | MGI:1914988 | Organism | mouse, laboratory |
Chromosome | 3 | NCBI Gene Number | 67738 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable several functions, including cyclosporin A binding activity; heat shock protein binding activity; and nuclear estrogen receptor binding activity. Predicted to be involved in several processes, including cellular response to UV-A; positive regulation of viral genome replication; and protein peptidyl-prolyl isomerization. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in cytosol. Is expressed in embryo. Orthologous to human PPID (peptidylprolyl isomerase D). PHENOTYPE: Mice homozygous for a prolyl isomerase dead version of the protein dispay abnormal mitochondrial function and increased susceptibility to myocardial ischemic injury. [provided by MGI curators] |