| Primary Identifier | MGI:1346342 | Organism | mouse, laboratory |
| Chromosome | 3 | NCBI Gene Number | 23844 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable intracellularly calcium-gated chloride channel activity. Predicted to be involved in several processes, including calcium ion transport; cellular response to hypoxia; and chloride transmembrane transport. Predicted to act upstream of or within chloride transport. Located in membrane; microvillus; and secretory granule. Is expressed in genitourinary system; heart; intestine; retina; and thymus. Human ortholog(s) of this gene implicated in asthma and chronic obstructive pulmonary disease. Orthologous to human CLCA1 (chloride channel accessory 1). PHENOTYPE: Mice homozygous for a null allele exhibit an exacerbated mucin response. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
