| Primary Identifier | MGI:1351315 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 27224 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to be involved in regulation of transcription by RNA polymerase II and transcription elongation by RNA polymerase II. Predicted to be located in site of DNA damage. Predicted to be part of elongin complex. Is expressed in several structures, including central nervous system and genitourinary system. Orthologous to several human genes including ELOA (elongin A). PHENOTYPE: Embryos homozygous for a knock-out allele are severely growth retarded, exhibit a wide range of developmental anomalies and die between E10.5 and E12.5, most likely due to massive apoptosis while mutant MEFs show increased apoptosis and senescence-like growth defects. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
