| Primary Identifier | MGI:2387466 | Organism | mouse, laboratory |
| Chromosome | 4 | NCBI Gene Number | 269614 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable pantothenate kinase activity and phosphatase activity. Predicted to be involved in coenzyme A biosynthetic process and coenzyme A catabolic process. Predicted to be active in cytosol; extracellular space; and nucleus. Is expressed in several structures, including alimentary system; ear; genitourinary system; nervous system; and respiratory system. Used to study cataract. Human ortholog(s) of this gene implicated in cataract. Orthologous to human PANK4 (pantothenate kinase 4 (inactive)). PHENOTYPE: Mice homozygous for a null allele develop cataracts, with increased lens epithelial cell apoptosis, decreased lens epithelium thickness, and lens fiber abnormalities. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
