Primary Identifier | MGI:1313136 | Organism | mouse, laboratory |
Chromosome | 5 | NCBI Gene Number | 269713 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables microtubule plus-end binding activity. Predicted to be involved in cytoplasmic microtubule organization. Located in microtubule plus-end. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; limb; and trigeminal nerve. Used to study Williams-Beuren syndrome. Orthologous to human CLIP2 (CAP-Gly domain containing linker protein 2). PHENOTYPE: Mice homozygous and heterozygous for disruptions in this gene display growth deficiency, brain abnormalities and hippocampal dysfunction and deficits in motor coordination. [provided by MGI curators] |