| Primary Identifier | MGI:96175 | Organism | mouse, laboratory |
| Chromosome | 6 | NCBI Gene Number | 15400 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables DNA-binding transcription factor activity and HMG box domain binding activity. Acts upstream of or within several processes, including endocrine system development; regionalization; and skeletal system development. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; embryo mesenchyme; genitourinary system; gut; and nervous system. Used to study DiGeorge syndrome. Orthologous to human HOXA3 (homeobox A3). PHENOTYPE: Homozygotes for targeted null mutations are athymic, aparathyroid, and exhibit reduced thyroid and submaxillary glands, defects of the IXth nerve, and frequently, heart and artery abnormalities. Mutants die neonatally. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
