Primary Identifier | MGI:1861231 | Organism | mouse, laboratory |
Chromosome | 6 | NCBI Gene Number | 56620 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables carbohydrate binding activity and pattern recognition receptor activity. Involved in several processes, including positive regulation of canonical NF-kappaB signal transduction; positive regulation of immune response; and response to fungus. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including adipose tissue; bone; immune system; liver; and lung. Orthologous to human CLEC6A (C-type lectin domain containing 6A). PHENOTYPE: Mice homozygous for a null allele have defective responses to Candida albicans. [provided by MGI curators] |