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Protein Coding Gene : Klrb1c killer cell lectin-like receptor subfamily B member 1C
Primary Identifier  MGI:107538 Organism  mouse, laboratory
Chromosome  6 NCBI Gene Number  17059
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables identical protein binding activity and signaling receptor activity. Acts upstream of or within natural killer cell activation and positive regulation of natural killer cell mediated cytotoxicity. Located in external side of plasma membrane. Is expressed in thymus primordium. Orthologous to human KLRB1 (killer cell lectin like receptor B1).
PHENOTYPE: This locus controls an antigen on natural killer cells. The a allele determines the Nk1.1 antigen in strains CE, C57BL/6, C57BR/cd, C57L, C58, DBA/1, MA/My, NZB, SJL, SM and B10.D2. The b allele determines the Nk1.2 antigen in strains CBA/J, BALB/c, C3H/He, A/J, DBA/2, LP and 129. [provided by MGI curators]
  • synonyms:
  • natural killer cell-associated antigen 1,
  • Nk1,
  • MGD-MRK-12044,
  • Nkrp1-c,
  • Klrb1c,
  • NKR-P1,
  • Ly-59,
  • AI462337,
  • MGD-MRK-12001,
  • NKR-P1C,
  • killer cell lectin-like receptor subfamily B member 1C,
  • MGD-MRK-12881,
  • Nk1.1,
  • CD161,
  • MGI:97344,
  • lymphocyte antigen 55 complex, locus C,
  • MGI:96879,
  • NK-RP1,
  • expressed sequence AI462337,
  • MGI:2141422,
  • Nk-1.2,
  • Ly59,
  • lymphocyte antigen 59,
  • Nk-1,
  • MGD-MRK-36108,
  • MGD-MRK-12883,
  • NK-1.1,
  • Ly55c
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