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Protein Coding Gene : Csnk2a2 casein kinase 2, alpha prime polypeptide

Primary Identifier  MGI:88547 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  13000
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0)

Enables protein serine/threonine kinase activity. Acts upstream of or within protein phosphorylation; regulation of cell cycle; and spermatogenesis. Predicted to be located in acrosomal vesicle and chromatin. Predicted to be part of PcG protein complex and protein kinase CK2 complex. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study male infertility. Orthologous to human CSNK2A2 (casein kinase 2 alpha 2).
PHENOTYPE: Males homozygotes for a targeted null mutation of the minor catalytic subunit exhibit infertility with oligospermia and abnormally shaped spermatid nuclei. [provided by MGI curators]
  • synonyms:
  • MGI:2142847,
  • CK2,
  • expressed sequence C77789,
  • casein kinase 2, alpha prime polypeptide,
  • Csnk2a2,
  • 1110035J23Rik,
  • MGI:1915939,
  • RIKEN cDNA 1110035J23 gene,
  • C77789,
  • MGD-MRK-2205

Features --> Cross References

Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

40 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

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0 Driver For