| Primary Identifier | MGI:1926923 | Organism | mouse, laboratory |
| Chromosome | 8 | NCBI Gene Number | 63857 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Enables beta-carotene 15,15'-dioxygenase activity. Involved in carotene catabolic process and retinal metabolic process. Acts upstream of or within beta-carotene metabolic process. Predicted to be located in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; hemolymphoid system gland; nervous system; and sensory organ. Orthologous to human BCO1 (beta-carotene oxygenase 1). PHENOTYPE: Mice homozygous for a null mutation display fatty livers, elevated serum free fatty acid levels, increased susceptibility to diet-induced obesity, and impaired conversion of beta-carotene to vitamin A. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
