| Primary Identifier | MGI:104979 | Organism | mouse, laboratory |
| Chromosome | 9 | NCBI Gene Number | 12797 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable actin filament binding activity. Predicted to be involved in actin filament organization and negative regulation of vascular associated smooth muscle cell proliferation. Predicted to be located in cytoskeleton. Predicted to be active in actin cytoskeleton. Is expressed in several structures, including cardiovascular system; genitourinary system; gut; hemolymphoid system gland; and lung. Orthologous to human CNN1 (calponin 1). PHENOTYPE: Mice homozygous for an allele lacking exons 5-7 exhibit accelerated cartilage formation and ossification. As adults mutant animals have increased width of the long bones and accelerated bone fracture repair. Mice homozygous for an allele lacking intron 1exhibit preweaning lethality. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
