| Primary Identifier | MGI:1277988 | Organism | mouse, laboratory |
| Chromosome | X | NCBI Gene Number | 22294 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 8.0.0) Predicted to enable beta-tubulin binding activity; chromatin binding activity; and transcription corepressor activity. Predicted to be involved in centrosome cycle and negative regulation of transcription by RNA polymerase II. Predicted to be located in several cellular components, including centrosome; chromatin; and nucleus. Predicted to be part of RPAP3/R2TP/prefoldin-like complex and mediator complex. Is expressed in several structures, including cerebellum; neural retina; and telencephalon. Orthologous to human UXT (ubiquitously expressed prefoldin like chaperone). PHENOTYPE: Mice hemizygous or heterozygous for a germline null mutation display prenatal lethality. Male mice with testes-specific conditional loss of expression display azoospermia. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
