| Primary Identifier | MGI:1856035 | Allele Type | Spontaneous |
| Gene | Axin1 | Inheritance Mode | Semidominant |
| Strain of Origin | Bussey Institution stock | Is Recombinase | false |
| Is Wild Type | false |
| description | Gametic imprinting has been detected for Axin1Fu (J:11139), and the locus may be affected by inherited inactivation (J:6577). Penetrance is affected by the genetic background, although expressivity is not. A suppressor gene in C57BL/6 decreases the penetrance of Axin1Fu in hybrids (J:11139). The suppressor gene did not affect penetrance of Axin1Fu in mice chimeric between C57BL/6 and a stock carrying Axin1Fu (J:19657). |
| molecularNote | The mutation is an IAP retrotransposon insertion within the sixth intron that results in the production of wild-type transcripts as well as mutant transcripts that initiate at both the authentic promoter and the 3'-most long terminal repeat of the insertion. |
