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Allele : Apc<Min> APC, WNT signaling pathway regulator; multiple intestinal neoplasia

Primary Identifier  MGI:1856318 Allele Type  Chemically induced (ENU)
Gene  Apc Inheritance Mode  Dominant
Strain of Origin  C57BL/6J Is Recombinase  false
Is Wild Type  false
molecularNote  A transversion point mutation that alters nucleotide 2549 from a T to an A (mRNA: NM_001360980.1; protein: NM_007462.3). This converts codon 850 from one encoding a leucine to a stop codon (p.Leu850*), truncating the expected polypeptide.
  • mutations:
  • Single point mutation
  • synonyms:
  • Apc<delta850>,
  • Apc<&Delta;850>,
  • Min,
  • Apc<delta850>,
  • Apc<580S>,
  • Apc<->,
  • Min,
  • Apc<->,
  • Apc<&Delta;850>,
  • Apc<580S>,
  • Min-,
  • Min-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

33 Carried By

0 Driven By

1000 Publication categories