| Primary Identifier | MGI:1857024 | Allele Type | Spontaneous |
| Gene | Fzd6 | Inheritance Mode | Recessive |
| Strain of Origin | English fancy stock | Is Recombinase | false |
| Is Wild Type | false |
| description | Found in a strain from an English fancier. Penetrance in homozygotes appears to be complete, but expression is variable. The most common expression is two whorls, each centered on a hindleg and extending mid-dorsally and almost mid-ventrally (J:15067). |
| molecularNote | A spontaneous missense mutation, c.1061G>A (AGC>ATC codon change in exon 4), results in a serine-to-isoleucine substitution at amino acid 354 of the encoded protein (p.S354I), which affects hair growth pattern. |
