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Allele : Agt<tm1Unc> angiotensinogen; targeted mutation 1, University of North Carolina

Primary Identifier  MGI:1857121 Allele Type  Targeted
Attribute String  Null/knockout Gene  Agt
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
description  Human AGT and renin genes can complement the effects of the mouse null mutation (J:39934).
molecularNote  A genomic fragment within exon 2 that codes for 114 amino acids of the encoded protein was replaced with a neomycin selection cassette. Radioimmunoassay tests confirmed that no protein was detectable in plasma of homozygous mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • AGT-,
  • AGT-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

24 Publication categories