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Allele : Agt<tm2Unc> angiotensinogen; targeted mutation 2, University of North Carolina

Primary Identifier  MGI:1857122 Allele Type  Targeted
Gene  Agt Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
description  Human AGT and renin genes can complement the effects of the mouse null mutation (J:39934).
molecularNote  A tandem duplication of the gene was created by "gap-repair" gene targeting. Radioimmunoassay tests demonstrated increased plasma levels of the encoded protein in heterozygous mice.
  • mutations:
  • Duplication
  • synonyms:
  • Tg(Agtdup)1Unc,
  • Agt<TgH(Agtdup)1Unc>,
  • Agt<TgH(Agtdup)1Unc>,
  • TgH(Agtdup)1Unc,
  • TgH(Agtdup)1Unc,
  • Tg(Agtdup)1Unc
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1 Feature

Genome

0 Expresses

1 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

10 Publication categories