Primary Identifier | MGI:1857122 | Allele Type | Targeted |
Gene | Agt | Transmission | Germline |
Strain of Origin | 129P2/OlaHsd | Is Recombinase | false |
Is Wild Type | false |
description | Human AGT and renin genes can complement the effects of the mouse null mutation (J:39934). |
molecularNote | A tandem duplication of the gene was created by "gap-repair" gene targeting. Radioimmunoassay tests demonstrated increased plasma levels of the encoded protein in heterozygous mice. |