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Allele : Fcer1g<tm1Rav> Fc receptor, IgE, high affinity I, gamma polypeptide; targeted mutation 1, Jeffrey V Ravetch
Primary Identifier  MGI:1857165 Allele Type  Targeted
Attribute String  Null/knockout Gene  Fcer1g
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette was inserted into exon 2, creating a new stop codon 239 bp downstream of the integration site. RT-PCR analysis on RNA isolated from activated macrophages, mast cells and NK cells of homozygous mice demonstrated that no detectable transcript was produced from this allele. Western blot analysis on lysates derived from activated macrophages, mast cells and NK cells of homozygous mice confirmed that no protein is encoded by this allele.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • FcRgamma-chain<->,
  • Fcer1g<tm1>,
  • FcRgamma<nl>,
  • FcR gamma<->,
  • gamma-,
  • FcRgamma<nl>,
  • FcR-,
  • FcRKO,
  • Fcerg1<tm1>,
  • Fcerg1<tm1>,
  • FcRgammac<->,
  • FcR gamma<->,
  • FcR-,
  • FcRgamma-chain<->,
  • FcRg<->,
  • Fcepsilonrgamma<->,
  • Fcer1g<tm1Ra>,
  • FcRgamma-,
  • Fcer1g<tm1Ra>,
  • Fcepsilonrgamma<->,
  • FcRgammac<->,
  • FcgammaR-,
  • FcRgamma-,
  • FcRg<->,
  • Fcer1g<tm1>,
  • FcRKO,
  • gamma-,
  • FcgammaR-,
  • Fcer1g<tm1>,
  • FcRgamma-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

9 Carried By

0 Driven By

385 Publication categories





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