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Allele : Gabra6<tm1Geh> gamma-aminobutyric acid type A receptor subunit alpha 6; targeted mutation 1, Gregg E Homanics

Primary Identifier  MGI:1857173 Allele Type  Targeted
Attribute String  Null/knockout Gene  Gabra6
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette was inserted into exon 8. Northern blot analysis on RNA derived from cerebellum of homozygous mice demonstrated that aberrant transcripts were expressed from this allele. Hoever, none of these are predicted to be able to code for a functional protein (J:40242). Later studies showed that this mutation also affected the expression of the Gabra1 and Gabrb2 genes (J:63792).
  • mutations:
  • Insertion
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

6 Publication categories