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Allele : Prf1<tm1Sdz> perforin 1 (pore forming protein); targeted mutation 1, Sandoz Pharmaceuticals
Primary Identifier  MGI:1857235 Allele Type  Targeted
Attribute String  Null/knockout Gene  Prf1
Transmission  Germline Strain of Origin  C57BL/6
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin selection cassette was inserted into exon 3. RT-PCR analysis on RNA derived from homozygous mice demonstrated that an abnormal transcript was produced from this allele. However, immunocytochemistry experiments on activated spleen cells derived from homozygous mice confirmed that no detectable protein was made from this allele.
  • mutations:
  • Insertion
  • synonyms:
  • perf-,
  • Pfn<->,
  • P<0>,
  • perforin-,
  • pfp-,
  • pko,
  • Pfp<tm1Sdz>,
  • Prf1<tm/Sdz>,
  • pfpKO,
  • prf1<tm1>,
  • Prf<->,
  • Prf<->,
  • perf-,
  • Pfn<->,
  • P<0>,
  • perforin 0,
  • pko,
  • Prf1<tm/Sdz>,
  • Prf1<->,
  • perforin 0,
  • prf1<tm1>,
  • Pfp<tm1Sdz>,
  • perforin-,
  • Prf1<->,
  • pfp-,
  • pfpKO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

20 Carried By

0 Driven By

368 Publication categories





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