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Allele : Rbl2<tm1Tyj> RB transcriptional corepressor like 2; targeted mutation 1, Tyler Jacks
Primary Identifier  MGI:1857449 Allele Type  Targeted
Attribute String  Null/knockout Gene  Rbl2
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced sequences in a proximal exon of the Rbl2 gene. Rbl2 mRNA levels in liver cells of homozygous mutant animals were reduced more than five fold compared to wild-type. Immunoblot analysis did not detect RBL2 protein in embryonic fibroblasts or in adult liver of homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • p130-,
  • p130-
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

34 Publication categories





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