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Allele : Fgf2<tm1Doe> fibroblast growth factor 2; targeted mutation 1, Thomas Doetschman

Primary Identifier  MGI:1857458 Allele Type  Targeted
Attribute String  Null/knockout Gene  Fgf2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  An Hprt minigene replaced 0.5kb of sequence containing 121bp of the proximal promoter region and exon 1. Northern blot analysis of E13.5 embryos demonstrated that no mRNA containing exon 2 and 3 sequences is detectable in homozygous mutant mice. Western blot analysis on brain tissue from homozygous mutant mice showed that the protein is absent.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • FGF-2<->,
  • FGF-2<->,
  • Fgf2-,
  • Fgf2-
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

57 Publication categories

Trail: Allele