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Allele : Cd1<tm1Gru> CD1 antigen complex; targeted mutation 1, Michael Grusby
Primary Identifier  MGI:1857482 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cd1
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  Both the Cd1d1 gene and the adjacent Cd1d2 gene were mutated in this allele. The coding sequence of Cd1d1 was replaced with a neomycin selection cassette and the coding sequence of Cd1d2 was deleted; however, the intergenic sequence was retained. Flow cytometric analysis on thymocytes derived from homozygous mice confirmed that no stable encoded protein was expressed on the cell surface.
  • mutations:
  • Intergenic deletion,
  • Insertion
  • synonyms:
  • Cd1d1/Cd1d2<tm1Gru>,
  • CD1<->,
  • Cd1d<->,
  • CD1tm1Gru,
  • Cd1d1/Cd1d2<tm1Gru>,
  • CD1d KO,
  • CD1<->,
  • Cd1d<->,
  • CD1tm1Gru,
  • CD1d KO
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1 Feature

Genome

0 Expresses

2 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

0 Driven By

129 Publication categories





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