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Allele : Edn1<tm1Utj> endothelin 1; targeted mutation 1, University of Tokyo
Primary Identifier  MGI:1857637 Allele Type  Targeted
Attribute String  Null/knockout Gene  Edn1
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance gene was inserted into exon 2, which encodes the mature peptide. RT-PCR analysis on RNA derived from homozygous embryos demonstrated that no detectable transcript was produced from this allele. Enzyme immunoassay tests confirmed that no active peptide was present in lung extracts of homozygous mice.
  • mutations:
  • Insertion
  • synonyms:
  • ET-1<->,
  • EdnRA<->,
  • ET-1<->,
  • EdnRA<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

34 Publication categories





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