Primary Identifier | MGI:1857762 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Cnr1 |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | false | Is Wild Type | false |
molecularNote | This Cnr1 mutation was created by gene targeting in which a neo cassette replaced amino acids 33-447 of the coding region (J:54995). A neomycin resistance cassette replaced genomic sequence coding for amino acids 33-447, corresponding to most of the coding sequence of the gene. Absence of the encoded protein in homozygous animals was confirmed by receptor binding studies. |