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Allele : Cnr1<tm1Zim> cannabinoid receptor 1; targeted mutation 1, Andreas Zimmer

Primary Identifier  MGI:1857762 Allele Type  Targeted
Attribute String  Null/knockout Gene  Cnr1
Transmission  Germline Strain of Origin  129S2/SvPas
Is Recombinase  false Is Wild Type  false
molecularNote  This Cnr1 mutation was created by gene targeting in which a neo cassette replaced amino acids 33-447 of the coding region (J:54995). A neomycin resistance cassette replaced genomic sequence coding for amino acids 33-447, corresponding to most of the coding sequence of the gene. Absence of the encoded protein in homozygous animals was confirmed by receptor binding studies.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • CB1<neor>,
  • Cb1<->,
  • CB1R KO,
  • CB1R KO,
  • CB1<neor>,
  • Cnr1-,
  • Cnr1-,
  • Cb1<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

154 Publication categories