| Primary Identifier | MGI:1857500 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Rbl2 |
| Transmission | Germline | Strain of Origin | 129S4/SvJae |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Insertion of a PGK neomycin resistance cassette into an exon disrupted the Rbl2 gene. Northern analysis of homozygous mutant embryos (E14) using a full length Rbl2 cDNA probe did not detect Rbl2 mRNA. Immunoblot analysis using antisera reactive with the carboxyl-terminal 20 amino acids of RBL2 did not detect RBL2 in homozygous mutant embryos. |
