| Primary Identifier | MGI:1857933 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Pgr |
| Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neomycin cassette was inserted into the first exon and downstream from the initiating codons that encode the A and B isoforms to effectively disrupt transcription of both isoforms. Northern analysis indicated a lack of gene specific transcript. Competitive binding assays for the progesterone receptor indicated a lack a functional protein in homozygous mutant animals. |
