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Allele : Lat<tm1Les> linker for activation of T cells; targeted mutation 1, Lawrence E Samelson
Primary Identifier  MGI:1857812 Allele Type  Targeted
Attribute String  Null/knockout Gene  Lat
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A neomycin resistance cassette replaced ~3.9 kb of sequence containing exons 1 - 8 of the gene, which encode amino acids 1 - 169 of the protein. No protein for the targeted gene was detected on immunoblots of lysates of thymocytes from homozygous mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • LAT<KO>,
  • LAT<->,
  • LAT<->,
  • LAT<KO>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

45 Publication categories





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